Sugar-sweetened Beverages Increased the Risk of Gout

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If you have hyperuricemia or gout, you should stop or reduce your intake of sugar-sweetened sodas, orange juice, and fructose, according to new research published online November 10 in the Journal of the American Medical Association. 

The data comes from the Nurses’ Health Study, which looked at the intake of beverages and its relationship to gout in 78,906 women from 1984 to 2006. 

Compared with the consumption of less than 1 serving per month of sugar-sweetened soda, the consumption of 1 serving per day was associated with a 1.74-fold increased risk for gout, and the consumption of 2 or more servings per day was associated with a 2.39-fold increased risk. 

Consumption of orange juice was associated with a 1.41-fold and 2.42-fold increased risk for 1 and 2 servings per day, respectively. 

The consumption of diet soft drinks, however, was not associated with the risk for gout. 

The effect of fructose (sugar used to sweeten the beverages) on the pathology of gout is well known.  As it is been shown before, intake of fructose to human subjects resulted in a rapid increase in serum uric acid and increased purine synthesis. 

Source: JAMA. Published online November 10, 2010.  Abstract. 

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