Tag Archives: progression-free survival

New Monoclonal Antibodies Increased Survival in Lung Cancer Patients

A new study showed that non-small-cell lung cancer (NSCLC) patients who have high level of Met proteins in their tumor can have their survival increase three-fold by receiving experimental antibody MetMAb in combination with erlotinib (Tarceva).  In the trial, 137 previously-treated … Continue reading

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New Personalized Medicine Increases Survival in Melanoma Patients

Metastatic melanoma is the deadliest and most aggressive from of skin cancer.  A person with metastatic melanoma typically has a short life expectancy that is measured in months.   The mainstay treatments for metastatic melanoma are dacarbazine (DTIC), interleukin-2 (IL-2) and … Continue reading

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Bevacizumab Beneficial in Newly Diagnosed Glioblastoma?

A large study of patients with newly diagnosed glioblastoma multiforme suggests that the addition of bevacizumab (Avastin) and irinotecan (Camptosar) to standard chemoradiation can extend survival (progression and overall survival) by 6 months.  Bevacizumab (Avastin) is an inhibitor of vascular … Continue reading

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Afatinib Extend Time to Tumor Progression in Advanced Lung Cancer

Currently, no treatment exists for lung cancer patients with epidermal growth-factor receptor (EGFR) mutation who have failed tyrosine kinase inhibitors, getifinib (Iressa) or erlotinib (Tarceva).  However, an investigational drug, afatinib (BIBW 2992), was recently found to increase progression-free survival and … Continue reading

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Europe Approved Sutent for Rare Pancreatic Cancer

The European Commission has recently approved Sutent (sunitinib) as a medicine for treating patients with pancreatic neuroendocrine tumors (NET).   The drug is now indicated to treat unresectable metastatic, well-differentiated pancreatic NET in adults with disease progression.  The approval was based … Continue reading

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